Testosterone
Testosterone is a hormone that is produced by both males and females which acts as a chemical messenger throughout the body. Testosterone is produced in
Autoimmune rheumatic diseases
Written by: Solaris Diagnostics
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ANAs are a class of antibodies that bind to cellular components in the nucleus including proteins, DNA, RNA, and nucleic acid-protein complexes. The origin of ANA testing was first described in 1948 when Hargraves and colleagues observed the LE cells, described as mature polymorphonuclear leukocyte containing phagocytosed nuclear material. LE cells were so named because there were found only in patient with systemic lupus erythematosus (SLE). Since then, ANA identification remains the most sensitive serologic marker for evaluation of patients with suspected connective tissue autoimmune disorders including systemic lupus erythematosus (SLE), Sjogren’s syndrome, and polymyositis/dermatomyositis. Although 20-30% of the average population has detectable levels of ANAs, increased titers are characteristic of individuals with connective tissue disorders. The table shows the rhematic disease associated with a positive ANA test.
Solaris Diagnostics laboratory can now provide screening for ANA with turnaround time of 24 hours from the time the sample is received in the laboratory.
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