Knowledge Center

The Calcium Assay

The Calcium Assay is an in vitro test used for the quantitative determination of calcium in human serum, plasma, and urine. Calcium holds vital roles in muscle contraction, hormone secretion, glycogen metabolism, bone mineralization, nerve impulse transmission, and blood coagulation. Detection of abnormal blood calcium levels may assist in the diagnosis of variety of issues

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Uncategorized

The Anti-Thyroid Peroxidase assay

The Anti-Thyroid Peroxidase assay is an in vitro test used for the quantitative determination of autoantibodies against thyroid peroxidase in human serum and plasma. The enzyme thyroid peroxidase (TPO) is integral to normal thyroid function as it allows for thyroid hormone synthesis. However, anti-thyroid peroxidase antibodies (aTPO) may be produced by the immune system in

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Uncategorized

Autoimmune rheumatic diseases

Autoimmune rheumatic diseases are conditions in which the immune system attacks the joints and certain system. They are often difficult to diagnose as their symptoms can be vague, vary from patient to patient, and often overlap with other clinical conditions. The diagnosis of autoimmune disease is based on patient signs and symptoms, clinical information, and

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Hematology

Erythrocyte sedimentation rate

Erythrocyte sedimentation rate Erythrocyte sedimentation rate, otherwise known as a sed rate, is an in vitro test that is used as a marker of inflammation. ESR is the rate in mm/hour at which red blood cells in an anticoagulated standardized tube settle from plasma and other blood components. The standardized tube typically used for this

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Special Chemistry

Apolipoprotein A-1 (APO A) and Apolipoprotein B (APO B)

Apolipoprotein A-I (apo A-I) is the major structural and functional protein component of high-density lipoprotein (HDL), or good cholesterol in plasma. It accounts for approximately 70% of HDL. Apo A-I activates lecithin cholesterol acyltransferase (LCAT) which catalyzes the esterification of cholesterol. The resulting esterified cholesterol can then be transported to the liver, metabolized, and excreted.

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RT-PCR

Importance of PCR in identification of urinary tract infection

The status and future direction of advanced urine testing: multiplex PCR- published on March 7, 2023 from Urology Times highlights that the importance of PCR in identification of Urinary tract infection. The article discuss the approach used by Solaris Diagnostics along with some other laboratories in the industry. The standard urine culture (SUC) has several

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