Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Rheumatoid factors are autoantibodies directed against the Fc portion of IgG. They are most commonly IgM, but IgG and IgA RFs may also occur. RF is present in the serum of most patients with rheumatoid arthritis (RA), though detection rates vary by method: latex bead assays coated with human IgG are positive in 70–85% of patients but may give more false positives, while sheep RBC assays coated with rabbit IgG are positive in 60–70% with fewer false positives.
RF is not specific to RA and can occur in other rheumatic or chronic inflammatory conditions. Low-titer RF can also be detected in healthy individuals, particularly with increasing age, with IgM RF reported in up to 10% of the general population. High RF titers in RA are associated with more severe disease and systemic involvement. RF can also be found in synovial, pleural, and pericardial fluids, though serum testing is the main diagnostic tool. Some RFs may behave as cryoglobulins.
References:
Arnett FC et al. Arthritis Rheum. 1988;31:315–324.
Smolen JS et al. Lancet. 2016;388:2023–2038.
Nishimura K et al. Ann Rheum Dis. 2007;66:158–163.
Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.
Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.
CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.
For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.
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