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Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Syphilis is an STI that is typically transmitted through contact with someone’s infected sores during unprotected sex. The syphilis bacterium is called treponema pallidum. It enters the body through mucous membranes or cuts or abrasions on the skin.
Syphilis has four stages. Each has its own set of symptoms. If untreated, syphilis can become deadly. Early treatment can cure syphilis completely before symptoms worsen.
The Rapid Plasma Reagin (RPR) Test is a non-Treponemal Flocculation Test. It detects and quantifies reagin, an antibody present in people with syphilis or other treponemal diseases.
RPR measures IgM and IgG antibodies to lipodial materials released from damaged host cells as well as lipoprotein like material and possibly cardiolipin released from treponems.
Treponema pallidum, the etiologic agent responsible for syphilis, produces at least two kinds of antibodies in human infections. These two kinds are treponemal antibodies and the reagin antibody.
Autoantibodies are produced in 2-3 weeks of treponemal infection due to tissue damage. These auto antibodies are often referred to as cardiolipin antibodies because they can be detected in serological test using cardiolipin antigen.
This test doesn’t look for antibodies against actual bacterium but rather for antibodies against substances released by cells they are damaged by Treponema pallidum.
The anti-lipodial antibodies are antibodies that are not produce only in syphilis infection but also in other non treponemal disease of an acute and chronic nature in which tissues are damaged.
Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.
Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.
CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.
For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.
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