Total Iron Binding Capacity (TIBC)

CPT: 83550

Expected Turnaround Time

24 Hours

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Serum

Container

SST (Serum), Red Top (Separate Serum)

Storage Instructions

Room Temp., Refrigerated (2-8 C)

Stability Requirements

Room temp. 72hrs., Refrigerated 7 days

Test Details

Additional Information

Total Iron-Binding Capacity (TIBC) is a way to find the maximum amount of iron the blood can carry. Iron is an especially important mineral that the body needs to make hemoglobin, which is a protein in the red blood cells that helps transport oxygen from the lungs to the rest of the body. TIBC does not measure the actual amount of iron in the body, but instead, it checks how much iron the blood can potentially carry. This test is often used to check iron levels in the body and to spot possible iron-related issues. 

High TIBC levels might mean the body is working extra hard to make up for not having enough iron. This could happen for a few reasons, like not getting enough iron from food or having trouble absorbing iron due to pregnancy. Some medications and long-term health issues can also alter how the body handles iron, leading to higher TIBC levels. Conditions like iron deficiency anemia, where the body cannot make enough oxygen-carrying hemoglobin due to low iron, could also cause high TIBC levels. 

A low TIBC result means the body might not be able to carry and use iron as effectively as it should. This could happen for various reasons, such as the body not getting enough nutrients, having inflammation, or having a genetic condition that affects how the body handles iron.  

Certain medications, like those that impact iron absorption or metabolism, could also play a role. Sometimes, low TIBC levels might be connected to issues like liver disease or hypoproteinemia, which is when the body has unusually low levels of proteins in the blood. A low TIBC does not necessarily mean the body is lacking iron, but it does suggest that the body might be struggling to make the most of the iron it has.

Footnotes

  1. Waldvogel-Abramowski S, Waeber G, Gassner C, Buser A, Frey BM, Favrat B, Tissot JD. Physiology of iron metabolism. Transfus Med Hemother. 2014 Jun;41(3):213-21. [PMC free article] [PubMed] 
  2. Dev S, Babitt JL. Overview of iron metabolism in health and disease. Hemodial Int. 2017 Jun;21 Suppl 1(Suppl 1):S6-S20. [PMC free article] [PubMed] 

Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.

Questions?

For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.