Vitamin B12

Written by: Solaris Diagnostics

Doctor sitting and a table with a patient discussing vitamin B12. Patients hands are folded on the table.

The Vitamin B12 assay is an in vitro test used for the quantitative determination of Vitamin B12 in human serum and plasma. Vitamin B12 is necessary for DNA synthesis, cellular energy production, and red blood cell production. Vitamin B12 deficiency was introduced in 1849 and was originally thought to be fatal. This changed in 1926 when it was discovered that a diet high in B12 could combat the disease process. Vitamin B12 is produced by gut bacteria in animals and then absorbed by those animals. As a result, Vitamin B12 is found in animal tissues and a diet high in B12 includes foods like liver, eggs, and dairy.

High levels of vitamin B12 may be due to multivitamin consumption or even pregnancy, oral contraceptive use, and myeloproliferative disease including chronic granulocytic leukemia and myelomonocytic leukemia. Low levels of vitamin B12 may aid in the diagnosis of vitamin-dependent anemia. Vitamin B12 monitoring is typically used for individuals with vitamin B12 deficiency, as high levels of vitamin B12 are not known to be harmful. In addition to a diet lacking vitamin B12, a deficiency may be caused by pernicious anemia, a disease in which a lack of Intrinsic Factor causes deficiency, and other intestinal diseases that affect absorption including celiac disease. Vitamin B12 deficiency is seen more often in the elderly, as well as vegetarians. A deficiency has also been linked to cognitive decline, bone health, and vision loss in the elderly.

At Solaris Diagnostics, Vitamin B12 is measured using direct chemiluminescent technology. The test method requires an assay-specific reagent, acid, and base in order to generate a chemiluminescent reaction. During analysis, a luminometer measures the light emitted from the reaction as Relative Light Units (RLUs) and the software converts the RLUs to results. Solaris Diagnostics can provide results within 24 hours from the time the sample is received in the laboratory.

Sources:
https://lnkd.in/drexQJuB
https://lnkd.in/dPFCPHFr
https://lnkd.in/dNcVWhBn


Benefits of Working with Solaris Diagnostics

Now you can provide patients with the quickest and most accurate diagnosis possible from our high-complexity, CLIA accredited laboratory. Choose Solaris Diagnostics for:

  • Simple collection
  • Results by 5:00 pm on the day the lab receives the specimen
  • Direct access to experienced scientific staff
  • Among the most personal customer service experiences in the industry

Our experts assist clinicians and health care providers in rapidly identifying the pathogens and underlying causes of disease. We know that fast and accurate diagnoses lead to better patient outcomes.

For more information call 844-550-0308 to speak with one of our staff. You may also use the form on our Contact Us page.

 

Share this Article

Share on linkedin
Share on facebook
Share on twitter
Share on email
Share on print

Recent Articles

Uncategorized

MecA

Antibiotic resistance is a serious topic in the medical community, as new drugs are developed and used for the treatment of infections these bacteria have

Read More »
RT-PCR

Chlamydia Trachomatis

April is STI Awareness Month. The stigma surrounding sexually transmitted infections often leads to them not being talked about, and therefore, not being proactively dealt

Read More »
PT/INR

PT/INR

The prothrombin time (PT) is the most commonly used anticoagulant test and was first introduced into use by Dr. Armand Quick and colleagues in 1935.^1

Read More »
Uncategorized

Conjunctivitis

Conjunctivitis is a term describing inflammation of the superficial tissue (conjunctiva) of the eye. It can be either infectious or non-infectious. Infectious causes can be viral or

Read More »
Doctor looking over test results at a desk with medicine.
RT-PCR

MRSA

Methicillin-Resistant Staphylococcus Aureus (MRSA) is a gram-positive bacteria that is resistant to the penicillin family of antibiotics. Staphylococcus aureus is a common bacteria that causes

Read More »
Uncategorized

Cortisol Assay

Cortisol, a steroid hormone, is synthesized from cholesterol. It is synthesized in the zona fasciculata layer of the adrenal cortex. Cortisol has many functions in

Read More »

Need a Reliable Diagnostic Partner?

At Solaris Diagnostics, we make it easy!

Our Results Portal allows you access patient reports quickly and securely online.

To request access to the Providers Results Portal, please complete our Provider Registration form.

Scroll to Top