Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Apolipoprotein B (ApoB) is the primary apolipoprotein associated with atherogenic lipoproteins, serving as the structural and transport protein for chylomicrons, very-low-density lipoprotein (VLDL), intermediate-density lipoprotein (IDL), low-density lipoprotein (LDL), and lipoprotein(a). It is not found in high-density lipoproteins (HDL), which instead contain apolipoprotein A (Apo A). There are two main isoforms of ApoB in circulation: ApoB-100, synthesized in the liver, and ApoB-48, synthesized in the small intestine. Both forms are encoded by the same gene, but differ due to post-transcriptional RNA editing. ApoB-100 has a molecular weight of approximately 540,000 Da and consists of 4,536 amino acids; it is essential for the assembly of VLDL and serves as the ligand for LDL receptor-mediated uptake of LDL particles by cells. ApoB-48, which comprises the N-terminal 48% of ApoB-100 (2,152 amino acids), is required for the formation of chylomicrons and plays a key role in the absorption of dietary lipids in the intestine.
References
Devaraj S, Semaan JR, Jialal I. Biochemistry, Apolipoprotein B. [Updated 2023 May 14]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK538139/
Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.
Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.
CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.
For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.
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