Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Urine creatinine is measured to assess renal excretory function and to normalize the concentration of other analytes in spot urine samples. It is typically quantified using enzymatic or kinetic Jaffe methods on automated chemistry analyzers. Urine creatinine is essential in calculating the creatinine clearance (CrCl), which provides an estimate of glomerular filtration rate (GFR) when paired with serum creatinine and a timed urine collection—most commonly over 24 hours. It is also used to validate the completeness of 24-hour urine collections and to standardize measurements such as urine protein-to-creatinine or albumin-to-creatinine ratios. Low urine creatinine levels may suggest dilute urine, poor collection, or impaired renal function, while elevated levels may be seen in concentrated urine or increased muscle mass. Interpretation must consider age, sex, body mass, and hydration status.
References:
Perrone, R. D., Madias, N. E., & Levey, A. S. (1992). Serum creatinine as an index of renal function: new insights into old concepts. Clinical Chemistry, 38(10), 1933–1953. https://doi.org/10.1093/clinchem/38.10.1933
Nolin, T. D., Himmelfarb, J., & Komodo, C. A. (2009). Estimating renal function in the pharmacokinetic evaluation of renally eliminated drugs. Clinical Pharmacokinetics, 48(6), 387–400. https://doi.org/10.2165/00003088-200948060-00001
Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.
Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.
CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.
For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.
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