CRP (High Sensitive)

CPT: 86141

Expected Turnaround Time

24 Hours

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements


Serum, Plasma


SST (Serum), Red Top (Separate Serum), Lithium Heparin (Plasma), EDTA (Plasma)

Storage Instructions

Room Temp., Refrigerated (2-8 C)

Stability Requirements

Room temp. 7 days, Refrigerated 7 days

Test Details

Additional Information

High-sensitivity CRPs or HSCRPs are variations of regular CRPs that are more easily detected by common medical tests. Technically, HSCRPs aren’t different types of proteins altogether. Instead, these proteins are simply the easiest for tests to measure, which makes them effective markers of inflammation to be used with overall wellness tests or tests that check for specific issues like cardiovascular disease (CVD).

C-reactive protein (CRP) is produced by the liver. Its level rises when there’s inflammation in the body. LDL cholesterol not only coats the walls of the arteries, but it also damages them. This damage causes inflammation that the body tries to heal by sending a “response team” of proteins called “acute phase reactants.” CRP is one of these proteins.  

C-reactive protein (hsCRP) is a blood test that measures low levels of C-reactive protein (CRP), which indicates general inflammation levels in the body. The hsCRP test is more sensitive than the standard CRP test, which measures high levels of the protein to identify different diseases that cause inflammation. The hsCRP test can help determine the risk of cardiovascular disease (CVD). High levels of hsCRP in the blood have been linked to an increased risk of heart attacks, stroke, peripheral arterial disease, and sudden cardiac death 


  1. Wilson PWF, et al. Overview of established risk factors for cardiovascular disease. Accessed April 13, 2021. 
  2. Hart, P.C., et al. C-reactive protein and cancer—diagnostic and therapeutic insights. (2020) 

Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.


For questions or inquiries related to testing please reach out to or contact us by phone at (844) 550-0308.