Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.
Hepatitis B Core Antibody, Total (anti-HBc Total) detects both IgM and IgG antibodies to the hepatitis B core antigen and is used to identify previous or ongoing infection with hepatitis B virus (HBV). Unlike surface antigen or antibody markers, anti-HBc is not present following vaccination alone and indicates natural exposure to the virus. A positive anti-HBc Total result suggests past or current infection but does not distinguish between acute and chronic stages unless IgM-specific testing is also performed. In acute infection, anti-HBc appears shortly after HBsAg and often persists for life. This marker is especially useful during the “window period” when HBsAg has cleared but anti-HBs has not yet developed. Interpretation should always be in the context of other serologic markers (HBsAg, anti-HBs, anti-HBc IgM) to determine infection status.
References
Terrault, N. A., Lok, A. S. F., McMahon, B. J., Chang, K. M., Hwang, J. P., Jonas, M. M., … & Yawn, B. P. (2018). Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance. Hepatology, 67(4), 1560–1599. https://doi.org/10.1002/hep.29800
Centers for Disease Control and Prevention (CDC). (2024). Hepatitis B questions and answers for health professionals. Retrieved from https://www.cdc.gov/hepatitis/hbv/hbvfaq.htm
Hollinger, F. B., & Liang, T. J. (2001). Hepatitis B virus. In D. M. Knipe & P. M. Howley (Eds.), Fields Virology (4th ed., pp. 2971–3036). Lippincott Williams & Wilkins.
Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.
Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.
CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.
For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.
Contact Information
Helpful Links
