Human Growth Hormone (HGH)

CPT: 83003

Expected Turnaround Time

24 Hours

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Serum

Volume

5 ml

Minimum Volume

25 ul

Container

SST (Serum), Red Top (Serum)

Storage Instructions

Room Temp., Refrigerated (2-8 C)

Stability Requirements

Room temp. 7 days, Refrigerated 7 days

Causes for Rejection

Incorrect labeling, frozen gel-barrier tube, mislabeled samples, QNS

Test Details

Use

This test is use for the quantitative measurement of human growth hormone in serum, as an aid in patient management.

Methodology

chemiluminescent immunometric

Additional Information

Human Growth Hormone (hGH), also known as somatotropin, is a peptide hormone secreted by the anterior pituitary gland that plays a critical role in growth, metabolism, and cellular regeneration. hGH stimulates linear bone growth in children and adolescents and also affects muscle mass, fat metabolism, and glucose homeostasis. Testing for hGH is used primarily to diagnose growth hormone deficiency in children with short stature or in adults with suspected pituitary disorders. It may also be used to evaluate growth hormone excess, as seen in conditions like acromegaly or gigantism.

References

Grinspoon, S. K., & Biller, B. M. (1994). Clinical review 62: Laboratory assessment of growth hormone secretion in adults with pituitary disease. The Journal of Clinical Endocrinology & Metabolism, 79(2), 377–387. https://doi.org/10.1210/jcem.79.2.8045953

Molitch, M. E., Clemmons, D. R., Malozowski, S., Merriam, G. R., & Vance, M. L. (2011). Evaluation and treatment of adult growth hormone deficiency: An Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 96(6), 1587–1609. https://doi.org/10.1210/jc.2011-0179

Allen, D. B., Cuttler, L. (2013). Short stature in childhood—Challenges and choices. New England Journal of Medicine, 368(13), 1220–1228. https://doi.org/10.1056/NEJMra1203394

Footnotes

Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.

Questions?

For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.