Wound Panel Complete

CPT: 87640, 87651, 87798×13

Test Includes

Antibiotic Resistance Test Menu 

  • ampC 
  • CTX-M Group 1 
  • CTX-M Group 2 
  • ErmA 
  • ErmB 
  • femA 
  • IMP-7 
  • KPC 
  • mecA 
  • mefA 
  • NDM 
  • OXA-48 
  • QnrA 
  • QnrB 
  • SHV 
  • TEM 
  • vanA1 
  • vanA2 
  • vanB 
  • VIM 

  Bacteria Targets 

  • Acinetobacter baumannii 
  • Bacteroides fragilis 
  • Citrobacter freundii 
  • Clostridium novyi 
  • Clostridium perfringens 
  • Clostridium septicum 
  • Enterobacter aerogenes 
  • Enterobacter cloacae 
  • Enterococcus faecalis 
  • Enterococcus faecium 
  • Escherichia coli 
  • Kingella Kingae 
  • Klebsiella oxytoca 
  • Klebsiella pneumoniae 
  • Morganella morganii 
  • Proteus mirabilis 
  • Proteus vulgaris 
  • Pseudomonas aeruginosa 
  • Staphylococcus aureus 
  • Streptococcus pyogenes (Strep A) 

Expected Turnaround Time

24 hours

Turnaround time is defined as the usual number of days from the date of pickup of a specimen for testing to when the result is released to the ordering provider. In some cases, additional time should be allowed for additional confirmatory or additional reflex tests. Testing schedules may vary.

Specimen Requirements

Specimen

Wound Swab

Container

Liquid Amies Medium with Polyster Flock Swab

Storage Instructions

Room Temp., Refrigerated (2-8 C)

Stability Requirements

Room temp 5 Days, Refrigerated 5 Days

Test Details

Methodology

PCR

Additional Information

Chronic wounds, such as diabetic ulcers, present significant challenges in terms of morbidity and disability. Their delayed healing process is influenced by various factors, including age, the stage of diabetic disease, medication adherence, peripheral neuropathy, immune system compromise, and circulatory issues like arterial and venous insufficiency. These wounds often fail to progress through the typical healing trajectory, posing a substantial and increasing problem exacerbated by modern sedentary lifestyles, rising obesity rates, and the prevalence of diabetes. 

Moreover, Chronic wounds also contain polymicrobial infections existing as a cooperative community that resist conventional antibiotic treatments. Traditional wound culture methods have limitations in accurately capturing the microbial complexity within these wounds. They may overlook certain organisms or fail to fully represent their interactions. This bias can obscure a comprehensive understanding of the microbial landscape within the wound. While culture techniques may identify predominant bacteria, they often miss those present in lower quantities, which could still contribute to the chronicity of the wound. 

In contrast, advanced molecular diagnostic techniques, such as wound PCR (polymerase chain reaction), offer a promising solution for more rapid and thorough assessment. Unlike culture methods, PCR can detect a broader spectrum of microorganisms, including those present in smaller numbers. This capability provides a more comprehensive overview of the microbial community within chronic wounds, facilitating targeted and effective treatment strategies. Thus, molecular diagnostics holds significant potential for improving the management of chronic wounds and ultimately enhancing patient outcomes. 

 

References

  1. Tatum OL, Dowd SE. Wound Healing Finally Enters the Age of Molecular Diagnostic Medicine. Adv Wound Care (New Rochelle). 2012 Jun;1(3):115-119. doi: 10.1089/wound.2011.0303. PMID: 24527290; PMCID: PMC3839019. 
  2. Li S, Renick P, Senkowsky J, Nair A, Tang L. Diagnostics for Wound Infections. Adv Wound Care (New Rochelle). 2021 Jun;10(6):317-327. doi: 10.1089/wound.2019.1103. Epub 2020 Jul 7. PMID: 32496977; PMCID: PMC8082727. 
  3. Ding X, Tang Q, Xu Z, Xu Y, Zhang H, Zheng D, Wang S, Tan Q, Maitz J, Maitz PK, Yin S, Wang Y, Chen J. Challenges and innovations in treating chronic and acute wound infections: from basic science to clinical practice. Burns Trauma. 2022 May 21;10:tkac014. doi: 10.1093/burnst/tkac014. PMID: 35611318; PMCID: PMC9123597. 
  4. CopyDownload .nbib 
  5. Rhoads DD, Wolcott RD, Sun Y, Dowd SE. Comparison of culture and molecular identification of bacteria in chronic wounds. Int J Mol Sci. 2012;13(3):2535-2550. doi: 10.3390/ijms13032535. Epub 2012 Feb 23. PMID: 22489109; PMCID: PMC3317672. 

Footnotes

Statement on Medical Necessity
All ordered tests should be medically necessary for the diagnosis or detection of disease, illness, impairment, symptom, syndrome, or disorder and the results should be used in the medical management and treatment decisions for the patient. Solaris requires ICD-10 codes with each order for lab testing and both the tests ordered and the diagnosis should be documented in the provider’s medical record for the patient. The United States Department of Health and Human Services, Office of Inspector General, takes the position that a provider who orders medically unnecessary tests may be subject to civil penalties.

Panels and Profiles
Solaris offers Providers the convenience of ordering test combinations in a group at times with the flexibility to choose appropriate test(s) for individual patients. Providers should only order those tests that he or she believes are medically necessary for each patient, and a lesser inclusive profile or individual tests should be ordered if not all tests in the test combination/profile are medically necessary. All tests offered in a test combination/profile may be ordered separately as individual tests. Solaris encourages clients to contact their Solaris representative if the testing configurations shown do not meet individual needs for any reason, or if some other combination of procedures is needed.

CPT Codes
CPT Codes listed are in accordance with Current Procedural Terminology, a publication of the American Medical Association. CPT codes are the responsibility of the billing party and are listed here for informational purposes. Correct coding may vary from one carrier to another. Solaris may bill specific carriers using codes other than what is shown.

Questions?

For questions or inquiries related to testing please reach out to
customerservice@solarisdx.com or contact us by phone at (844) 550-0308.